What is ALS?
Amyotrophic lateral sclerosis (ALS), often referred to as "Lou Gehrig's Disease," is a progressive neurodegenerative disease that affects nerve cells in the brain and the spinal cord.
Motor neurons reach from the brain to the spinal cord and from the spinal cord to the muscles throughout the body. The progressive degeneration of the motor neurons in ALS eventually leads to their death. When the motor neurons die, the ability of the brain to initiate and control muscle movement is lost. With voluntary muscle action progressively affected, patients in the later stages of the disease may become totally paralyzed.
A-myo-trophic comes from the Greek language. "A" means no or negative. "Myo" refers to muscle, and "Trophic" means nourishment-"No muscle nourishment." When a muscle has no nourishment, it "atrophies" or wastes away. "Lateral" identifies the areas in a person's spinal cord where portions of the nerve cells that signal and control the muscles are located. As this area degenerates it leads to scarring or hardening ("sclerosis") in the region.
As motor neurons degenerate, they can no longer send impulses to the muscle fibers that normally result in muscle movement. Early symptoms of ALS often include increasing muscle weakness, especially involving the arms and legs, speech, swallowing or breathing. When muscles no longer receive the messages from the motor neurons that they require to function, the muscles begin to atrophy (become smaller). Limbs begin to look "thinner" as muscle tissue atrophies.
5,000+
people are diagnosed per year
2-5 Years
is the average life expectancy
Only 10%
of cases are inherited through a mutated gene
According to the American Academy of Neurology's Practice Parameter Update, studies have shown that participation in a multidisciplinary ALS clinic may prolong survival and improve quality of life.
Amyotrophic Lateral Sclerosis (ALS), commonly known as Lou Gehrig's Disease, is a devastating neurodegenerative disease that progressively weakens muscle control by affecting nerve cells in the brain and spinal cord. Each year, over 5,000 individuals are diagnosed, facing challenges that can lead to severe physical limitations within 2-5 years. Despite these hurdles, ALS United Chicago is dedicated to providing care and support. Our multidisciplinary clinics and comprehensive care services aim to improve the quality of life for those touched by ALS. Through advocacy, research funding, and community engagement, we strive to make a significant impact. Together, we can contribute to a future where ALS can be effectively managed or ultimately cured.