ALS Research Innovation Program
Advancing Cutting-Edge Projects that Accelerate Therapy Development
ALS Research Innovation Program
The ALS Network, a member of ALS United, has partnered with other ALS United member organizations to launch an initiative to directly fund research. Together, we are powering progress to cure ALS.
The ALS Research Innovation Program provides innovation grants to fund novel yet scientifically rigorous ideas that can transform our understanding of ALS. Our seed funding to establish proof of concept for new scientific approaches potentially positions these visionary projects for larger-scale funding in the future, such as government grants. In addition, our nimble “pitch session” approach to vet unique projects accelerates the application process, removing red-tape and moving promising science forward faster.
Still in its first year, the ALS Research Innovation Program has established a world-class Scientific Advisory Committee, approved four projects for funding, and funded two of the four approved projects. (The other two approved projects are currently in the contracting phase with funds to be dispersed accordingly.) A public-facing Request for Proposals launches in spring of 2025 and will significantly expand the portfolio of funded projects.
- Our Approach -
Strategic investment of funds with Scientific Advisory Committee review and oversight. Fuel moonshot; power an efficient, collaborative research framework designed to de-risk investment and accelerate the search for effective prevention strategies, treatments, and cures for ALS.
Strategic collaborations with mission-aligned individuals and entities. Stakeholders include scientists, corporate partners, academic institutions, nonprofit organizations, and others.
Strategic partnership with an inclusive, diverse, informed, and engaged community- including people diagnosed with ALS, caregivers, and family members.
Priority
Areas
- Curing sporadic ALS
- Treating asymptomatic gene carriers
- Identifying and addressing risk factors
Program Impact and Milestones
- Verify proof of concept for potential therapies
- Identify ALS biomarkers and risk factors
- Project-specific milestones to be developed by primary investigators
Funded
Projects
- Alpha-Synuclein and ALS Subtypes, Amprion
- Identification of Novel ALS Therapeutics: Reversing Abnormal RNA Processing and Stimulating Repair Mechanisms, AUTTX